1. Introduction Juvenile rhesus macaques commonly suffer from idiopathic chronic diarrhea (ICD). This disease is characterized by inflammation of the colon and repeated bouts of diarrhea. It is a common cause of morbidity and mortality among macaques because it is unresponsive to drugs. The gut microbiome of macaques with ICD is characterized by abrupt changes when compared to healthy individuals.
OmicsBox was used to perform the complete transcriptome analysis of Allium sativum. Enrichment analysis revealed important metabolic pathways.
This article describes how to run CloudBlast wisely. OmicsBox allows you to perform NCBI Blast searches using a cloud system for high-performance computing. This system runs jobs in parallel and autoscales depending on demand. To control usage we use so-called CloudUnits. These units represent computation time (cpu seconds) on the AWS infrastructure. At the moment only Blast and InterProScan consume
This project shows how OmicsBox was used to functional annotate Moringa oleifera and to better understand the genome of the plant.
Understanding the molecular differences that underlie the different COVID19 progression severity with Omic
OmicsBox Supported Project. Researchers: Hayden Waller, Cornell University, USA Background and Project Overview: One of the primary outcomes of speciation – the formation of new species – is the generation of pre-mating barriers that prevent or greatly reduce gene flow. Behavioral changes are perhaps the most potent in the early stages of speciation. In particular, the divergent evolution of sexual
De novo transcriptome assemblies are required to analyze RNA-seq data from a species for which there is no reference genome. However, with the advancement of next-generation sequencing technologies, the amount of available sequencing data is growing exponentially. Because of this, assembly algorithms often generate a large number of transcripts. Removing redundancy from such data could be crucial for reducing storage space,
Third-generation DNA sequencing technologies allows scientist to generate longer sequence reads, which can be used in whole-genome sequencing projects to yield better repeat resolution and more contiguous genome assemblies. However, although long-read sequencing technologies can produce genomes with long contiguity, the relatively high error rate of long reads has made it challenging to generate highly accurate final sequences. OmicsBox now
De novo transcriptome analysis in Datura metel and identification of genes related to withanolides biosynthesis pathway
BioBam Scholarship Supported Project – with OmicsBox. Researchers: Madhavi Hewadikaram Dr Sanjaya Deepal Bathige Prof. Veranja Karunaratne Project overview Withanolides are secondary plant compounds that belong to a family of C28 ergostane-type steroidal δ lactones that mainly belong to the family Solanaceae of the plant kingdom. Withanolides have held the interest and its importance in the scientific community owing to
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