The functional interpretation of differentially expressed genes obtained from RNA-seq data is a critical step in elucidating the intricate biological mechanisms underlying complex biological processes. Pathway analysis has emerged as a powerful approach to gaining insights into the coordinated interactions among genes within biological pathways. However, a major challenge in pathway analysis lies in the availability of annotation data, which
1. Introduction Juvenile rhesus macaques commonly suffer from idiopathic chronic diarrhea (ICD). This disease is characterized by inflammation of the colon and repeated bouts of diarrhea. It is a common cause of morbidity and mortality among macaques because it is unresponsive to drugs. The gut microbiome of macaques with ICD is characterized by abrupt changes when compared to healthy individuals.
Understanding the molecular differences that underlie the different COVID19 progression severity with Omic
OmicsBox Supported Project. Researchers: Hayden Waller, Cornell University, USA Background and Project Overview: One of the primary outcomes of speciation – the formation of new species – is the generation of pre-mating barriers that prevent or greatly reduce gene flow. Behavioral changes are perhaps the most potent in the early stages of speciation. In particular, the divergent evolution of sexual
BioBam Supported Project – with OmicsBox. Researchers: Dr. Abhishek Kumar, Computational Genome Biology Lab at Institute of Bioinformatics, Bangalore, India Project: The pandemic of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pushed the entire world on a halt with the largest lockdown of our times. A total numbers of infected cases are
BioBam Supported Project – with OmicsBox. Researchers: Richard Lathe – Division of Infection Medicine, University of Edinburgh Medical School, Edinburgh, UK Project: In managing the COVID-19 pandemic there is an urgent need to understand why some people develop severe infection leading to hospitalization and mortality, whereas others are relatively unaffected.
BioBam Supported Project – with OmicsBox. Researchers: Pr. Sami Aifa from the Laboratory of Molecular and Cellular Screening Processes (LPCMC) from the Centre of Biotechnology of Sfax, Tunisia Dr. Amor Mosbah from the Laboratory of Biotechnology and Valorization of Bio-Geo-Ressources (LBVBGR) from the Superior Institute of Biotechnology of Sidi Thabet, Tunisia Dr. Salma Abdeljalil and Pr. Ali Gargouri from the
BioBam Supported Project – with OmicsBox. Researchers: Luis Fernando Saraiva Macedo Timmers – Coordinator – Univates, Brazil Rafael Andrade Caceres – UFCSPA, Brazil Leandro de Mattos Pereira, UFRJ, Brazil Fernando Ruggiero Bachega – UFCSPA, Brazil Marcia Ines Goettert – Univates, Brazil Luiz Augusto Basso – PUCRS, Brazil Project: Currently, a large amount of data is available regarding the new SARS-CoV-2
In this use case we will use the metagenomics tools included in OmicsBox to analyze the microbial communities of two different soda lakes from Brazil. The original study was carried out by Ana P. D. Andreote, et al., 2018 (doi: 10.3389/fmicb.2018.00244). Introduction Soda lakes are special ecosystems found across Africa, Europe, Asia, etc. These lakes show high levels of sodium
Tips And Tricks
Helpful Features, Tips and Tricks
Use Cases, Reviews, Tutorials
Product Tutorial, Quickstarts, New Features, etc.