BioBam Supported Project – with OmicsBox.
Dr. Abhishek Kumar, Computational Genome Biology Lab at Institute of Bioinformatics, Bangalore, India
The pandemic of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pushed the entire world on a halt with the largest lockdown of our times. A total numbers of infected cases are 1,938,863 with 120,871 deaths (source: https://covid19stats.live/, by 14-April 2020).There is a massive urge of clinical solutions like vaccine development. Corona viruses have smaller genome of 30 kb size with 24 proteins. Yet several proteins are not properly annotated and characterised and often named as ORFs or CoV proteins. This hinders development of protein based vaccine development. Hence, there are needs for extensive re-annotation and characterisation of all proteins and their motives. The Computational Genome Biology Lab at Institute of Bioinformatics, Bangalore, India started now a genome-wide characterisations of CoV proteins and their motifs for potential roles as directed therapeutics. This study will assist in decision making for future vaccine development for COVID-19.
OmicsBox is a complete suite for genome analyses and annotations. It will assist us in rapid annotation and re-annotation of several CoVs and coming up for highly annotated solution for designing peptides.
This project is now supported with free access to all OmicsBox resources, including all modules and unlimited cloud computation.